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The target audience for JCMS includes laboratory technicians, animal colony managers, and principal investigators. 8600 Rockville Pike Colony Management AN EXTENSION OF YOUR LAB Our experts manage simple or complex projects on time and within budget. 2. Two ad-hoc report forms allow users to design their own reports from an extensive set of data filters and data output options (Fig. The user interfaces for JCMS have been implemented with the Microsoft Access Graphical User Interface (GUI) design tool and powered with program code written in Visual Basic for Applications Data loads are transactional, so either all valid records load correctly, or the entire transaction is rolled back. JBoss is a registered trademark and service mark of JBoss, Inc. Java is a registered trademark of Sun Microsystems, Inc.in the U.S. or other countries. JCMS meets the criteria for an ideal record-keeping system as outlined by Silver (1995), with additional functionality that supports the management of experimentally derived data as well as standard animal husbandry data. The extensibility of JCMS ensures that the system can adapt readily to changing user needs. Flexible query forms allow researchers to retrieve database records based on user-defined criteria. The software architecture for JCMS allows for addition of new functionality and enhancement of existing functions without major modifications to the basic application infrastructure. Then, in 1848, the "Fond-Gillarde" gallery, which cut the siderite vein after 160m, was dug. JAX Colony Management System (JCMS): an extensible colony and phenotype Zebrabase: An Intuitive Tracking Solution for Aquatic Model Organisms JCMS meets the criteria for an ideal record-keeping system as outlined by Silver (1995), with additional functionality that supports the management of experimentally derived data as well as standard animal husbandry data. Animal husbandry workflows are supported by form-driven user interfaces with controlled data entry points. 2007 Sep;131(1-2):3.e1-4. JAX Connect Function buttons are designed to support numerous workflows and are organized by task on the function bar. Samples can be associated with specific storage locations. If FIPS 140-2 encryption at the application level is not technically possible, FIPS 140-2 compliant full disk encryption (FOE) must be implemented on the hard drive where the DBMS resides. Most reports can be exported directly into Microsoft Excel for further analysis. PLoS Biol. London: Metheun & Co Ltd; 1959. Extensible open source content management systems and frameworks: a solution for many needs of a bioinformatics group. 1. Conditional Allele Mouse Planner (CAMP): software to facilitate the planning and design of breeding strategies involving mice with conditional alleles. Scand J Lab Animal Sci. Secondary responsibilities include removing unwanted data and transferring ownership of data records as needed. It is also possible for one owner to be a secretary of another owner, thereby having data edit capabilities for someone elses data. Three classes of cage cards are defined: (1) mating cards that list litter numbers and pertinent information about the parental mice in the mating (e.g., genotype, strain, and sex), (2) detail cards that list information about each individual mouse housed in a cage, and (3) wean cards that are designed for groups of mice housed together from the same litter. Data files must pass the preload test before loading into JCMS. Ideally, one would like to maintain records in a format that readily allows one to determine the relationship, if any, that exists between any two or more components of the colony, past or present. A number of software solutions have been implemented that are specifically designed for the management of animal husbandry and phenotyping data. The complete JCMS data model is included with the application. The JCMS database administrator is a named user called mtsadmin. Tutorials available on the web. The authors thank Dr. Anne Peaston and Susan Sheehan for critical discussion and review of the manuscript. Cage numbers printed on each card may be bar-coded and allow users to track information from the cage back to the database. The authors thank Dr. Anne Peaston and Susan Sheehan for critical discussion and review of the manuscript. An official website of the United States government. Per the May 5th, 2015 memorandum from the VA Chief Information Security Officer (CISO) FIPS 140-2 Validate Full Disk Encryption (FOE) for Data at Rest in Database Management Systems (DBMS) and in accordance with Federal requirements and VA policy, database management must use Federal Information Processing Standards (FIPS) 140-2 compliant encryption to protect the confidentiality and integrity of VA information at rest at the application level. Cage numbers printed on each card may be bar-coded and allow users to track information from the cage back to the database. Typical animal husbandry workflow supported by JCMS. For larger cohorts, we offer an IVF Expansion Service. The JCMS Pedigree Tracking Tool (JPT) The JCMS tool suite includes a separate application called the JCMS Pedigree Tracking tool that connects to any JCMS database and graphically displays pedigree trees (Fig. Epub 2007 Dec 5. JCMS Reports and Queries JCMS provides extensive reporting capabilities for colony managers and investigators conducting experiments. BR_WR0002 has three parent mouse records (trio mating): HH-W0002, HH-W0003, and HH-W0004. User support for JCMS is provided through a group email list and a monitored community electronic discussion forum (http://community.jax.org/forums/default.aspx?GroupID=7). The Jackson Laboratory Colony ManagementSystem (JCMS) is a software application for managing dataand information related to research mouse colonies, asso-ciated biospecimens, and experimental. (Anything), but would not cover any version of 7.5.x or 7.6.x on the TRM. Aging Services An owner can edit his/her data but cannot edit other owners data. Macintosh users can also use Microsoft Windows PC virtualization software program such as Parallels or vmWare to run JCMS directly on a modern Intel Macintosh computer. The user community for the software has grown steadily since its initial release in 2005; there are currently over 900 active subscribers to the JCMS user support list. All instances of deployment using this technology should be reviewed to ensure compliance with, Veterans Affairs (VA) users must ensure VA sensitive data is properly protected in compliance with all VA regulations. 4). An overview of the three primary configurations for JCMS is shown in Fig. Once the software is configured and launched, the user is presented with a function bar that provides access to the software modules. The JCMS software application and associated tools and documentation are freely available from the project web site (http://colonymanagement.jax.org/). Future releases will include more vocabularies in the distribution such as terms from the mouse anatomical dictionary (http://www.informatics.jax.org/searches/anatdict_form.shtml). TopoDB: a novel multifunctional management system for laboratory animal colonies. Litter strain and breeding generation terms can be calculated to reduce the potential for data entry errors. My Account | The Jackson Laboratory, 610 Main Street, Bar Harbor, ME, 04609, USA, Chuck J. Donnelly,Mike McFarland,Abigail Ames,Beth Sundberg,Dave Springer,Peter Blauth&Carol J. Bult, You can also search for this author in The JCMS User Guide includes a section on Getting Started with JCMS that highlights key aspects of the setup process. In addition, data collected with such approaches are not amenable to searching, lack sophisticated data transaction controls, typically lack the use of controlled vocabularies or business rules, and are highly vulnerable to human error. Windows, Access, and Visual Basic are either registered trademarks or trademarks of Microsoft Corporation in the U.S. and/or other countries. JCMS employs a normalized relational data model that can be hosted on either Microsoft Access or MySQL databases. Clipboard, Search History, and several other advanced features are temporarily unavailable. Sundberg B, 8600 Rockville Pike . Transgenic Models DNA Microinjection 2019 Jun 20;17(6):e3000343. According to Silver (1995), An ideal record-keeping system would allow one to keep track of: (1) individual animals, their ancestors, siblings and descendants; (2) matings between animals; (3) litters born from such matings, and the individuals within litters that are used in experiments or to set up the next generation of matings; and (4) experimental material (tissues and DNA samples) obtained from individual animals. The report output fields are selected by check-box selection on the right side of the form. P Blauth The colony options include: Dedicated Colony:We can start with either frozen germplasm or live breeders (when available) to establish and maintain a dedicated colony of any JAX mouse. Genotype, sex, and strain information are also displayed for each mouse in the tree. MySQL is a registered trademark of MySQL AB in the U.S., the European Union, and other countries. Once the software is downloaded, the user is guided through the setup process. In this example query we have selected live mice with IDs that have EX in the name and are in the STOCK Igf1/ImJ strain. For example, a mating trio is entered into JCMS by selecting dams and sires from pulldown menus. Users must ensure sensitive data is properly protected in compliance with all VA regulations. The JCMS supports a simple security model that provides for three levels of security clearance for modifying existing data and/or adding new data records. JCMS is a freely available and supported research tool. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Posted 2:47:58 PM. Web-based user forums, Hosted solution. The Jackson Laboratory Colony Management System (JCMS) is a software application for managing data and information related to research mouse colonies, associated biospecimens, and experimental protocols. Once the software is downloaded, the user is guided through the setup process. TopoDB is built entirely with open-source software and can be extended and adapted to suit the needs of other laboratories, and even to manage other types of laboratory animals (either vertebrate or . JCMS is unique among the current offerings for colony management software because it is both free and well supported. JCMS can be configured for a single user or multiple users in small- to medium-size work groups. The relational data model that underlies JCMS minimizes data redundancy, enforces data integrity, leverages controlled vocabularies, and enables accurate data retrieval against large data sets. 2000;27:8492. 2015 Oct;26(9-10):467-81. doi: 10.1007/s00335-015-9586-7. Khorasani R, Lester JM, Davis SD, Hanlon WB, Fener EF, Seltzer SE, Adams DF, Holman BL. Some database entry steps (illustrated as rectangles with solid boarders) are required in the workflow to ensure the colony data are stored in the JCMS database, An example cage card for a cage holding three mice. Intel is a trademark of Intel Corporation in the U.S. and other countries. Web-based user forums, On-line videos and tutorials available upon registration. Correspondence to Home What is the JAX Colony Management program? JAX Colony Management System (JCMS): an extensible colony and phenotype data management system. (1) JCMS, Screen shots of the JCMS welcome page ( a ), main function bar, Typical animal husbandry workflow supported, Typical animal husbandry workflow supported by JCMS. Citrix is a trademark of Citrix Systems, Inc. and/or one or more of its subsidiaries, and may be registered in the U.S. Patent and Trademark Office and in other countries. JAX Colony Management System (JCMS): an extensible colony and phenotype The most flexible configuration, (3) shows JCMS accessible via the web and accessed from multiple operating system platforms (LINUX, Windows or Macintosh). Qasim Ali - Grenoble, Auvergne-Rhne-Alpes, France - LinkedIn It was discovered in 1767 by a shepherdess, who was going to throw a silver rich rock at a goat. TRM Proper Use Tab/Section. > Springer D, Through our facilities here, we can be an extension of your lab as we will start and maintain your colony for the duration of your project. Any wireless internet-capable device with appropriate user authentication capabilities running a middleware session client (such as Citrix) can run a JCMS session. Only mtsadmin can configure the security level for each GUI form. 2008 Jan;9(1):69-74. doi: 10.1093/bib/bbm057. According to Silver (1995), An ideal record-keeping system would allow one to keep track of: (1) individual animals, their ancestors, siblings and descendants; (2) matings between animals; (3) litters born from such matings, and the individuals within litters that are used in experiments or to set up the next generation of matings; and (4) experimental material (tissues and DNA samples) obtained from individual animals. JCMS also provides a number of precompiled work reports to help guide mouse-room activities, including weaning, timed matings, mouse line viability monitoring, and mouse testing. The JCMS Sample Tracking Module In JCMS, a sample is a unit of biological material associated with mouse, mating, or litter records in the database. For each mouse the JPT can optionally display sex, genotype, and strain information. To load experimental data into the database, users can use the bulk data-load operations in JCMS that support both flexible file format specification and preload data-checking scripts. 6). Web-based digital radiology teaching file: facilitating case input at time of interpretation. > Data on litters may be recorded at the time of birth or when the pups are weaned. The Jackson Laboratory Colony Management System (JCMS) is a software application for managing data and information related to research mouse colonies, associated biospecimens, and experimental protocols. Other colony management programs frequently have limited customization options or require costly subscriptions to use desirable features (Table 2). Illustration of the three primary installation configurations for the JCMS application. JCMS runs directly on computers that run one of the PC Windows operating systems, but can be accessed via web browser interfaces from any computer running a Windows, Macintosh, or Linux operating system. Data files must pass the preload test before loading into JCMS. 7). Please enable it to take advantage of the complete set of features! The highest level is the facility. The JCMS web site includes an online discussion forum for users that is monitored by the JCMS development team. Each secretary is associated with one or more owners. In the multi-user configuration examples, the black dots indicate that there may be any number of users, not just three users as depicted in the illustration, Typical animal husbandry workflow supported by JCMS. There are currently over 900 members subscribed to the email user group. The JCMS web site (http://colonymanagement.jax.org) provides access to several resources for JCMS users. The JCMS application is composed of four integrated software modules: (1) colony management, (2) experiment management, (3) sample tracking, and (4) reports and queries. Genotype, sex, and strain information are also displayed for each mouse in the tree. JAX -> NCBS (Imported for Prof. Upi Bhalla) JAX# 024109 : Homozygote x Homozygote, When maintaining a live colony, homozygous mice may be bred together. Animal models play a critical role in biomedical research because of their experimental tractability and their genetic and physiological similarity to humans. Designed for mouse and rat colony management, Designed specifically for workflows associated with transgenic animal production and gene knockout projects, Phone and email user support. JCMS runs directly on computers running a Windows operating system. The JCMS application is composed of four integrated software modules: (1) colony management, (2) experiment management, (3) sample tracking, and (4) reports and queries. The JCMS User Guide includes a section on Getting Started with JCMS that highlights key aspects of the setup process. JAX Colony Management System - The Jackson Laboratory Mouse Breeding Colony Management - University of Kentucky Our plans integrate known strain genotype, husbandry and phenotype details with the client's goals to insure the project timeline and budgets are well understood and executed on. Mamm Genome 21, 205215 (2010). The JCMS GUI enforces business rules and provides controlled access to the JCMS data. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. JCMS employs a normalized relational data model that can be hosted on either Microsoft Access or MySQL databases. [PDF] JAX Colony Management System (JCMS): An extensible colony and Animal husbandry workflows are supported by form-driven user interfaces with controlled data entry points. Search worldwide, life-sciences literature Search. Richmond J (2000) The 3Rspast, present and future. The most flexible configuration, (3) shows JCMS accessible via the web and accessed from multiple operating system platforms (LINUX, Windows or Macintosh). McFarland M, The main function bar and two of the JCMS data entry forms, Add Mouse and Edit Mouse, are shown in Fig. ES Cell Microinjection The relational data model that underlies JCMS minimizes data redundancy, enforces data integrity, leverages controlled vocabularies, and enables accurate data retrieval against large data sets. Preload data checking verifies that data records are complete, associated with mouse records, and have not already been loaded and that data values are within appropriate ranges. By donating your strain, you are protected against accidental loss and genetic contamination through cryopreservation. For example, a mating trio is entered into JCMS by selecting dams and sires from pulldown menus. JCMS owners are allowed to enter mice, matings, litters, experiments, samples, and any associated data. Principles and application of LIMS in mouse clinics. Advanced Search Coronavirus articles and preprints Search examples: "breast cancer" "breast cancer" BR_WR0002 has three parent mouse records (trio mating): HH-W0002, HH-W0003, and HH-W0004. Senior Control System Engineer - LinkedIn The Implementer of this technology has the responsibility to ensure the version deployed is 508-compliant. The Jackson Laboratory Colony Management System (JCMS) is a software application for managing data and information related to research mouse colonies, associated biospecimens, and experimental protocols.

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